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  Faculty

    Heejung Bang 
    Laurel Beckett 
    Danielle Harvey 
    Ana-Maria Iosif 
    Kyoungmi Kim 
    Chin-Shang Li 
    Diana L Miglioretti 
    Miriam Nuno 
    LiHong Qi 
    David Rocke 
    Susan L. Stewart 

  Staff

   Minh Chau (Chau) Barr
   Evan de Bie
   Blythe Durbin-Johnson
   Judy Li
   Lisa (Yi) Mu
   Vien Nguyen
   Naomi Saito
   Daniel Tancredi
   Sandra Taylor
   Machelle D Wilson
   Matt Yang

     

David Rocke

  Department Vice Chair, Distinguished Professor, PhD
  530-752-6999
  dmrocke@ucdavis.edu
  Dr. Rocke's personal webpage
Bioinformatics, design and analysis of gene expression, proteomics, and metabolomics data, analysis of mass spectrometry and NMR spectroscopy data, robust statistical methods.

Education
1972: Ph.D., Mathematics, University of Illinois, Chicago 
1966: A.B., Natural Sciences, Shimer College 

Courses Taught
EAD-115:  Numerical Methods for Engineering and Science Applications
EPP-245:  Statistical methods for laboratory data

Professional Affiliations/Awards
2007: Fellow, American Association for the Advancement of Science
1997: Elected Member, International Statistical Institute
1995: Fellow, American Statistical Association
1987: Shewell Award, Chemical and Process Industries Division, American Society for Quality Control
1985: Award for Interlaboratory Testing, American Statistical Association
1982: Youden Prize, Chemical Division, American Society for Quality Control

Selected Publications
  1. Stewart DN, Lango J, Nambiar KP, Falso MJ, FitzGerald PG, Rocke DM, Hammock BD, Buchholz BA. (2013). Carbon turnover in the water-soluble protein of the adult human lens. Molecular Vision, 19:463-75.

  2. Rice RH, Winters BR, Durbin-Johnson BP, Rocke DM. (2013). Chicken corneocyte cross-linked proteome. Journal of Proteome Research, 12(2):771-6.

  3. Rice RH, Bradshaw KM, Durbin-Johnson BP, Rocke DM, Eigenheer RA, Phinney BS, Schmuth M, Gruber R. (2013). Distinguishing ichthyoses by protein profiling. PLos One, 8(10):e75355.

  4. Mall C, Rocke DM, Durbin-Johnson B, Weiss RH. (2013). Stability of miRNA in human urine supports its biomarker potential. Biomarkers in Medicine, 7(4):623-31.

  5. Ray M, Yunis R, Chen X, Rocke DM. (2012). Comparison of low and high dose ionising radiation using topological analysis of gene coexpression networks. BMC Genomics, 13:190.

  6. Rice RH, Bradshaw KM, Durbin-Johnson BP, Rocke DM, Eigenheer RA, Phinney BS, Sundberg JP. (2012). Differentiating inbred mouse strains from each other and those with single gene mutations using hair proteomics. Plos One, 7(12):e51956.

  7. Yunis R, Albrecht H, Kalanetra KM, Wu S, Rocke DM. (2012). Genomic characterization of a three-dimensional skin model following exposure to ionizing radiation. Journal of Radiation Research, 53(6):860-75.

  8. Kitterman JA, Strober JB, Kan L, Rocke DM, Cali A, Peeper J, Snow J, Delai PL, Morhart R, Pignolo RJ, Shore EM, Kaplan FS. (2012). Neurological symptoms in individuals with fibrodysplasia ossificans progressiva. Journal of Neurology, 259(12):1636-43.

  9. Albrecht H, Durbin-Johnson B, Yunis R, Kalanetra KM, Wu S, Chen R, Stevenson TR, Rocke DM. (2012). Transcriptional response of ex vivo human skin to ionizing radiation: comparison between low- and high-dose effects. Radiation Research, 177(1):69-83.

  10. Fritz HM, Buchholz KR, Chen X, Durbin-Johnson B, Rocke DM, Conrad PA, Boothroyd JC. (2012). Transcriptomic analysis of toxoplasma development reveals many novel functions and structures specific to sporozoites and oocysts. PloS One, 7(2):e29998.

  11. Afify AM, Tate S, Durbin-Johnson B, Rocke DM, Konia T. (2011). Expression of CD44s and CD44v6 in lung cancer and their correlation with prognostic factors. The International Journal of Biological Markers, 26(1):50-7.

  12. Buchholz KR, Fritz HM, Chen X, Durbin-Johnson B, Rocke DM, Ferguson DJ, Conrad PA, Boothroyd JC. (2011). Identification of tissue cyst wall components by transcriptome analysis of in vivo and in vitro Toxoplasma gondii bradyzoites. Eukaryotic Cell, 10(12):1637-47.

  13. Romano PS, Marcin JP, Dai JJ, Yang XD, Kravitz RL, Rocke DM, Dharmar M, Li Z. (2011). Impact of public reporting of coronary artery bypass graft surgery performance data on market share, mortality, and patient selection. Medical Care, 49(12):1118-25.

  14. Barkauskas DA, Rocke DM. (2010). A general-purpose baseline estimation algorithm for spectroscopic data. Analytica Chimica Acta, 657(2):191-7.

  15. Chen Y, Wu R, Felton J, Rocke DM, Chakicherla A. (2010). A Method to Detect Differential Gene expression in Cross-Species Hybridization Experiments at Gene and Probe Level. Biomedical Informatics Insights, 2010(3):1-10.

  16. Kaplan FS, Zasloff MA, Kitterman JA, Shore EM, Hong CC, Rocke DM. (2010). Early mortality and cardiorespiratory failure in patients with fibrodysplasia ossificans progressiva. The Journal of Bone and Joint Surgery, 92(3):686-691.

  17. Maron JL, Johnson KL, Rocke DM, Cohen MG, Liley AJ, Bianchi DW. (2010). Neonatal salivary analysis reveals global developmental gene expression changes in the premature infant. Clinical Chemistry, 56(3):409-16.

  18. Barkauskas DA, Kronewitter SR, Lebrilla CB, Rocke DM. (2009). Analysis of MALDI FT-ICR mass spectrometry data: a time series approach. Analytica Chimica Acta, 648(2):207-14.

  19. Clermont G, Auffray C, Moreau Y, Rocke DM, Dalevi D, Dubhashi D, Marshall DR, Raasch P, Dehne F, Provero P, Tegner J, Aronow BJ, Langston MA, Benson M. (2009). Bridging the gap between systems biology and medicine. Genome Medicine, 1(9):88.

  20. Li B, Li D, Lau DH, Farwell DG, Luu Q, Rocke DM, Newman K, Courquin J, Purdy JA, Chen AM. (2009). Clinical-dosimetric analysis of measures of dysphagia including gastrostomy-tube dependence among head and neck cancer patients treated definitively by intensity-modulated radiotherapy with concurrent chemotherapy. Radiation Oncology (London, England), 4:52.

  21. Barkauskas DA, An HJ, Kronewitter SR, de Leoz ML, Chew HK, de Vere White RW, Leiserowitz GS, Miyamoto S, Lebrilla CB, Rocke DM. (2009). Detecting glycan cancer biomarkers in serum samples using MALDI FT-ICR mass spectrometry data. Bioinformatics, 25(2):251-257.

  22. Rice RH, Rocke DM, Tsai HS, Silva KA, Lee YJ, Sundberg JP. (2009). Distinguishing mouse strains by proteomic analysis of pelage hair. The Journal of Investigative Dermatology, 129(9):2120-5.

  23. Corbett BA, Constantine LJ, Hendren R, Rocke D, Ozonoff S. (2009). Examining executive functioning in children with autism spectrum disorder, attention deficit hyperactivity disorder and typical development. Psychiatry Research, 166(2-3):210-22.

  24. Martinelli F, Uratsu SL, Reagan RL, Chen Y, Tricoli D, Fiehn O, Rocke DM, Gasser CS, Dandekar AM. (2009). Gene regulation in parthenocarpic tomato fruit. Journal of Experimental Botany, 60(13):3873-90.

  25. Wheeler CA, Jafarzadeh SR, Rocke DM, Grodzinsky AJ. (2009). IGF-1 does not moderate the time-dependent transcriptional patterns of key homeostatic genes induced by sustained compression of bovine cartilage. Osteoarthritis and Cartilage, 17(7):930-8.

  26. Rocke DM, Ideker T, Troyanskaya O, Quackenbush J, Dopazo J. (2009). Papers on normalization, variable selection, classification or clustering of microarray data. Bioinformatics, 25(6):701.

  27. Berglund SR, Santana AR, Li D, Rice RH, Rocke DM, Goldberg Z. (2009). Proteomic analysis of low dose arsenic and ionizing radiation exposure on keratinocytes. Proteomics, 9(7):1925-38.

  28. Sivamani RK, Pullar CE, Manabat-Hidalgo CG, Rocke DM, Carlsen RC, Greenhalgh DG, Isseroff RR. (2009). Stress-mediated increases in systemic and local epinephrine impair skin wound healing: potential new indication for beta blockers. PLoS Medicine, 6(1):e12.

  29. Lu R, Lee GC, Shultz M, Dardick C, Jung K, Phetsom J, Jia Y, Rice RH, Goldberg Z, Schnable PS, Ronald P, Rocke DM. (2008). Assessing probe-specific dye and slide biases in two-color microarray data. BMC Bioinformatics, 9:314.

  30. Xi Y, Rocke DM. (2008). Baseline correction for NMR spectroscopic metabolomics data analysis. BMC Bioinformatics, 9:324.

  31. Zwienenberg-Lee M, Hartman J, Rudisill N, Madden LK, Smith K, Eskridge J, Newell D, Verweij B, Bullock MR, Baker A, Coplin W, Mericle R, Dai J, Rocke D, Muizelaar JP; Balloon Prophylaxis for Aneurysmal Vasospasm (BPAV) Study Group. (2008). Effect of prophylactic transluminal balloon angioplasty on cerebral vasospasm and outcome in patients with Fisher grade III subarachnoid hemorrhage: results of a phase II multicenter, randomized, clinical trial. Stroke, 39(6):1759-65.

  32. Jung KH, Dardick C, Bartley LE, Cao P, Phetsom J, Canlas P, Seo YS, Shultz M, Ouyang S, Yuan Q, Frank BC, Ly E, Zheng L, Jia Y, Hsia AP, An K, Chou HH, Rocke D, Lee GC, Schnable PS, An G, Buell CR, Ronald PC. (2008). Refinement of light-responsive transcript lists using rice oligonucleotide arrays: evaluation of gene-redundancy. PLos One, 3(10):e3337.

  33. Li Z, Kravitz RL, Marcin JP, Romano PS, Rocke DM, Denton TA, Brindis RG, Dai J, Amsterdam EA. (2008). Survival enhancing indications for coronary artery bypass graft surgery in California. BMC Health Services Research, 8:257.

  34. Marcin JP, Li Z, Kravitz RL, Dai JJ, Rocke DM, Romano PS. (2008). The CABG surgery volume-outcome relationship: temporal trends and selection effects in California, 1998-2004. Health Services Research, 43(1 Pt 1):174-92.

  35. Berglund SR, Rocke DM, Dai J, Schwietert CW, Santana A, Stern RL, Lehmann J, Hartmann Siantar CL, Goldberg Z. (2008). Transient genome-wide transcriptional response to low-dose ionizing radiation in vivo in humans. International Journal of Radiation Oncology*Biology*Physics, 70(1):229-34.

  36. Corbett BA, Kantor AB, Schulman H, Walker WL, Lit L, Ashwood P, Rocke DM, Sharp FR. (2007). A proteomic study of serum from children with autism showing differential expression of apolipoproteins and complement proteins. Molecular Psychiatry, 12(3):292-306.

  37. Ye J, Liu H, Kirmiz C, Lebrilla CB, Rocke DM. (2007). On the analysis of glycomics mass spectrometry data via the regularized area under the ROC curve. BMC Bioinformatics, 8:477.

  38. An HJ, Tillinghast JS, Woodruff DL, Rocke DM, Lebrilla CB. (2006). A new computer program (GlycoX) to determine simultaneously the glycosylation sites and oligosaccharide heterogeneity of glycoproteins. Journal of Proteome Research, 5(10):2800-8.

  39. Dai JJ, Lieu L, Rocke D. (2006). Dimension reduction for classification with gene expression microarray data. Statistical Applications in Genetics and Molecular Biology, 5:Article 6.

  40. Lehmann J, Stern RL, Daly TP, Rocke DM, Schwietert CW, Jones GE, Arnold ML, Siantar CL, Goldberg Z. (2006). Dosimetry for quantitative analysis of the effects of low-dose ionizing radiation in radiation therapy patients. Radiation Research, 165(2):240-7.

  41. Goldberg Z, Rocke DM, Schwietert C, Berglund SR, Santana A, Jones A, Lehmann J, Stern R, Lu R, Hartmann Siantar C. (2006). Human in vivo dose-response to controlled, low-dose low linear energy transfer ionizing radiation exposure. Clinical Cancer Research, 12(12):3723-9.

  42. German JB, Schanbacher FL, Lönnerdal B, Medrano JF, McGuire MA, McManaman JL, Rocke DM, Smith TP, Neville MC, Donnelly P, Lange M, Ward R. (2006). International milk genomics consortium. Trends in Food Science & Technology, 17(12):656-661.

  43. Rea MA, Zhou L, Qin Q, Barrandon Y, Easley KW, Gungner SF, Phillips MA, Holland WS, Gumerlock PH, Rocke DM, Rice RH. (2006). Spontaneous immortalization of human epidermal cells with naturally elevated telomerase. Journal of Investigative Dermatology, 126(11):2507.

  44. Rocke DM, Goldberg Z, Schweitert C, Santana A. (2005). A method for detection of differential gene expression in the presence of inter-individual variability in response. Bioinformatics, 21(21):3990-2.

  45. Aslam S, Rocke DM. (2005). A robust testing procedure for the equality of covariance matrices. Computational Statistics & Data Analysis, 49(3):863.

  46. Zhou L, Rocke DM. (2005). An expression index for Affymetrix GeneChips based on the generalized logarithm. Bioinformatics, 21(21):3983-9.

  47. Kitterman JA, Kantanie S, Rocke DM, Kaplan FS. (2005). Iatrogenic harm caused by diagnostic errors in fibrodysplasia ossificans progressiva. Pediatrics, 116(5):e654-61.

  48. Abel K, Rocke DM, Chohan B, Fritts L, Miller CJ. (2005). Temporal and anatomic relationship between virus replication and cytokine gene expression after vaginal simian immunodeficiency virus infection. Journal of Virology, 79(19):12164-72.

  49. Hardin J, Rocke DM . (2005). The distribution of robust distances. Journal of Computational and Graphical Statistics, 14(4):928-46.

  50. Dai J, Lorenzato S, Rocke DM. (2004). A Knowledge-Based Model for Watershed Assessment for Sediment. Environmental Modelling and Software, 19:423-33.

  51. Wilson MD, Ustin SL, Rocke DM. (2004). Classification of contamination in Salt Marsh plants using Hyperspectral data. IEEE Transactions on Geoscience and Remote Sensing, 42:1088-95.

  52. Rocke DM. (2004). Design and analysis of experiments with high throughput biological assay data. Seminars in Cell and Developmental Biology, 15(6):703-13.

  53. Wilson MD, Rocke DM, Durbin B, Kahn HD. (2004). Detection limits and goodness-of-fit measures for the two-component model of chemical analytical error. Analytica Chimica Acta, 509(2):197-208.

  54. Purohit PV, Rocke DM, Viant MR, Woodruff DL. (2004). Discrimination models using variance-stabilizing transformation of metabolomic NMR data. OMICS, 8(2):118-30.

  55. Scarlett RF, Rocke DM, Kantanie S, Patel JB, Shore EM, Kaplan FS. (2004). Influenza-like viral illnesses and flare-ups of fibrodysplasia ossificans progressiva. Clinical Orthopaedics and Related Research, 423:275-9.

  56. Nguyen DV, Rocke DM. (2004). On partial least squares dimension reduction for microarray-based classification: a simulation study. Computational Statistics & Data Analysis, 46(3):407.

  57. Hardin J, Rocke DM. (2004). Outlier detection in the multiple cluster setting using the minimum covariance determinant estimator. Computational Statistics & Data Analysis, 44(4):625-38.

  58. Durbin BP, Rocke DM. (2004). Variance-stabilizing transformations for two-color microarrays. Bioinformatics, 20(5):660-7.

  59. Rocke DM, Durbin B. (2003). Approximate variance-stabilizing transformations for gene-expression microarray data. Bioinformatics, 19(8):966-72.

  60. Purohit PV, Rocke DM. (2003). Discriminant models for high-throughput proteomics mass spectrometer data. Proteomics, 3(9):1699-703.

  61. Durbin B, Rocke DM. (2003). Estimation of transformation parameters for microarray data. Bioinformatics, 19(11):1360-7.

  62. Rocke DM, Durbin B, Wilson M, Kahn HD. (2003). Modeling Uncertainty in Analytical Measurements for Analysis of Bioavailability. Ecotoxicology and Environmental Safety, 56(1):78-92.

  63. Geller SC, Gregg JP, Hagerman P, Rocke DM. (2003). Transformation and normalization of oligonucleotide microarray data. Bioinformatics, 19(14):1817-23.

  64. Durbin BP, Hardin JS, Hawkins DM, Rocke DM. (2002). A variance-stabilizing transformation for gene-expression microarray data. Bioinformatics, 18(1 Suppl):S105-S110.

  65. Durbin B, Hardin J, Hawkins D, Rocke DM. (2002). A variance-stabilizing transformation for microarray data. Currents in Computational Molecular Biology, Liliana Florea, Brian Walenz, and Sridha:51-2.
    (extended abstract)

  66. Nguyen D, Rocke DM. (2002). Classification of acute leukemia based on DNA microarray gene expressions using partial least squares. Methods of Microarray Data Analysis, S. M. Lin and K. F. Johnson, eds.:109-124.
    Boston: Kluwer Academic

  67. Rocke DM, Woodruff DL. (2002). Computational connections between robust multivariate analysis and clustering. COMPSTAT 2002 Proceedings in Computational Statistics, Wolfgang Härdle and Bernd Rönz eds.(Heidelberg: Physica-Verlag):255-60.

  68. Zhao Y, Chen BP, Miao H, Yuan S, Li YS, Hu Y, Rocke DM, Chien S. (2002). Improved significance test for DNA microarray data: temporal effects of shear stress on endothelial genes. Physiological Genomics, 12(1):1-11.

  69. Geller S, Zhou L, Gregg J, Hagerman P, Rocke DM. (2002). Measurement error and reproducibility of affymetrix microarray data with application to autism. Currents in Computational Molecular Biology, Liliana Florea, Brian Walenz, and Sridha:68-9.
    (extended abstract)

  70. Nguyen DV, Rocke DM. (2002). Multi-class cancer classification via partial least squares with gene expression profiles. Bioinformatics, 18(9):1216-26.

  71. Jones G, Rocke DM. (2002). Multivariate survival analysis with doubly-censored data: application to the assessment of Accutane treatment for fibrodysplasia ossificans progressiva. Statistics in Medicine, 21(17):2547-62.

  72. Nguyen DV, Rocke DM. (2002). Partial least squares proportional hazard regression for application to DNA microarray survival data. Bioinformatics, 18(12):1625-32.

  73. Nguyen DV, Rocke DM. (2002). Tumor classification by partial least squares using microarray gene expression data. Bioinformatics, 18(1):39-50.

  74. Rocke DM, Durbin B. (2001). A model for measurement error for gene expression arrays. Journal of Computational Biology, 8(6):557-69.

  75. Jones G, Rocke DM. (2001). Analyte identification in multivariate calibration. Biometrics, 57(2):571-6.

  76. Nguyen DV, Rocke DM. (2001). Assessing patient survival using microarray gene expression data via partial least squares proportional hazard regression. Computing Science and Statistics, 33:376-89.

  77. Dai J, Rocke DM. (2000). Modeling spatial variation in area source emissions — A Poisson regression approach. Journal of Agricultural, Biological and Environmental Statistics,, 5:7-21.

  78. Leistikow BN, Martin DC, Jacobs J, Rocke DM, Noderer K. (2000). Smoking as a risk factor for accident death: a meta-analysis of cohort studies. Accident Analysis & Prevention, 32(3):397-405.

  79. Rocke DM. (1998). A perspective on statistical tools for data mining applications. Proceedings of the Second International Conference on Practical Application of Knowledge Discovery and Data Mining,:313-18.

  80. Glaser DL, Rocke DM, Kaplan FS. (1998). Catastrophic falls in patients who have fibrodysplasia ossificans progressiva. Clinical Orthopaedics and Related Research,(346):110-6.

  81. Hoover K, Yee JL, Schultz CM, Rocke DM, Hammock BD, Duffey SS. (1998). Effects of plant identity and chemical constituents on the efficacy of a Baculovirus against Heliothis Virescens. Journal of Chemical Ecology, 24:221-52.

  82. Rocke DM. (1998). Laboratory Quality Control. Encyclopedia of Biostatistics, New York(John Wiley)

  83. Sawyer JR, Klimkiewicz JJ, Iannotti JP, Rocke DM. (1998). Mechanism for superior subluxation of the glenohumeral joint in fibrodysplasia ossificans progressiva. Clinical Orthopaedics and Related Research,(346):130-3.

  84. Leistikow BN, Martin DC, Jacobs J, Rocke DM. (1998). Smoking as a risk factor for injury death: a meta-analysis of cohort studies. Preventive Medicine, 27(6):871-8.

  85. Zasloff MA, Rocke DM, Crofford LJ, Hahn GV, Kaplan FS. (1998). Treatment of patients who have fibrodysplasia ossificans progressiva with isotretinoin. Clinical Orthopaedics and Related Research,(346):121-9.

  86. Kaplan F, Sawyer J, Connors S, Keough K, Shore E, Gannon F, Glaser D, Rocke D, Zasloff M, Folkman J. (1998). Urinary basic fibroblast growth factor. A biochemical marker for preosseous fibroproliferative lesions in patients with fibrodysplasia ossificans progressiva. Clinical Orthopaedics and Related Research,(346):59-65.

  87. Jones G, Wortberg M, Rocke DM, Hammock BD. (1997). Immunoassay of cross-reacting analytes. Immunochemical Technology for Environmental Applications, D. S. Aga and E. M. Thurman, eds.:331-42.
    ACS Symposium Series No. 657, Washington, D.C.: American Chemical Society Publications.

  88. Rocke D, Jones G. (1997). Optimal Design for ELBA and Other Forms of Immunoassay. Technometrics, 39(2):162-170.

  89. Rocke DM, Woodruff DL. (1997). Robust estimation of multivariate location and shape. Journal of Statistical Planning and Inference, 57:245-5.

  90. Jones G, Wortberg M, Hammock BD, Rocke DM. (1996). A procedure for the immunoanalysis of samples containing one or more members of a group of cross-reacting analytes. Analytica Chimica Acta, 336:175-83.

  91. Wortberg M, Jones G, Kreissig SB, Rocke DM, Hammock BD. (1996). An approach to the construction of an immunoarray for differentiating and quantitating cross reacting analytes. Analytica Chimica Acta, 319:291-303.

  92. Jones G, Wortberg M, Kreissig SB, Hammock BD, Rocke DM. (1996). Application of the bootstrap to calibration experiments. Analytical Chemistry, 68(5):763-70.

  93. Rocke D, Woodruff D. (1996). Identification of Outliers in Multivariate Data. Journal of the American Statistical Association, 91(435):1047-1061.

  94. Downs GW, Rocke DM, Barsoom PN. (1996). Is the good news about compliance good news for cooperation? International Organization, 50:379-406.
    reprinted in International Institutions Lisa A Martin and Beth A Simmons, eds., 2001, Cambridge:MIT Press

  95. Rocke D. (1996). Robustness properties of S -estimators of multivariate location and shape in high dimension. Annals of Statistics, 24(3):1327-1345.

  96. Luchetti W, Cohen RB, Hahn GV, Rocke DM, Helpin M, Zasloff MA, Kaplan FS. (1996). Severe restriction in jaw movement following routine injection of local anesthetic in patients who have fibrodysplasia ossificans progressiva. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics, 1996(81)

  97. Rocke D, Lorenzato S. (1995). A Two-Component Model for Measurement Error in Analytical Chemistry. Technometrics, 37(2):176-184.

  98. Wortberg M, Kreissig SB, Jones G, Rocke DM, Hammock BD. (1995). An immunoarray for the simultaneous determination of multiple triazine herbicides. Analytica Chimica Acta, 304:339-52.

  99. Rocke DM. (1995). Optimal design of quantitative immunoassay protocols. New Frontiers in Agrochemical Immunoassay, David Kurtz, ed., Washington, DC: Association of Official Analytical Chemists,:251-259.

  100. George W. Downs and David M. Rocke. (1995). Optimal Imperfection? Domestic Uncertainty and Institutions in International Relations. Princeton: Princeton University Press, (Book)

  101. Lanchoney TF, Cohen RB, Rocke DM, Zasloff MA, Kaplan FS. (1995). Permanent heterotopic ossification at the injection site after diphtheria-tetanus-pertussis immunizations in children who have fibrodysplasia ossificans progressiva. The Journal of Pediatrics, 126(5 Pt 1):762-4.

  102. Kauvar LM, Higgins DL, Villar HO, Sportsman JR, Engqvist-Goldstein A, Bukar R, Bauer KE, Dilley H, Rocke DM. (1995). Predicting ligand binding to proteins by affinity fingerprinting. Chemistry & Biology, 2(2):107-18.

  103. Rocke DM, Pallas M. (1995). Prediction of automotive emissions from gasoline composition. Proceedings of the 1994 Spring Research Conference on Statistics in Industry and Technology, American Statistical Association,

  104. Jones G, Wortberg m, Kreissig SB, Hammock BD, Rocke DM. (1995). Sources of experimental variation in calibration curves for enzyme-linked immunosorbent assay. Analytica Chimica Acta, 313:197-207.

  105. Rocke DM, Zasloff M, Peeper J, Cohen RB, Kaplan FS. (1994). Age- and joint-specific risk of initial heterotopic ossification in patients who have fibrodysplasia ossificans progressiva. Clinical Orthopaedics and Related Research,(301):243-8.

  106. Woodruff DL, Rocke DM. (1994). Computable robust estimation of multivariate location and shape using compound estimators. Journal of the American Statistical Association, 89:888-96.

  107. Downs GW, Rocke DM. (1994). Conflict, agency, and gambling for resurrection: The principal-agent problem goes to war. American Journal of Political Science, 38:362-80.

  108. Jones G, Wortberg M, Kreissig SB, Bunch DS, Gee SJ, Hammock BD, Rocke DM. (1994). Extension of the four-parameter logistic model for ELISA to multianalyte analysis. Journal of Immunological Methods, 177(1-2):1-7.

  109. Rocke DM, Woodruff DL. (1994). Multivariate outlier detection. Proceedings of the 26th Symposium on the Interface: Computing Science and Statistics,:392-400.

  110. Woodruff D, Rocke DM. (1993). Heuristic search algorithms for the minimum volume ellipsoid. Journal of Computational and Graphical Statistics, 2:69-95.

  111. George W. Downs and David M. Rocke. (1990). Tacit Bargaining, Arms Races, and Arms Control. Ann Arbor: University of Michigan Press, (Book)

  112. Downs GW, Rocke DM. (1983). Designed experiments for classification problems. Journal of the Operational Research Society, 34(11):1069-77.

  113. Rocke DM. (1983). Robust statistical analysis of interlaboratory studies. Biometrika, 70(2):421-431.

  114. Rocke DM, Downs GW, Rocke AJ . (1982). Are robust estimators really necessary? Technometrics, 24(2):95-102.

  115. Downs GW, Rocke DM. (1980). Bureaucracy and juvenile corrections. Determinants of Public Policy, Thomas Dye and Virginia Gray, eds., Lexington MA: Heath-Lexington,

  116. Downs GW, Rocke DM. (1980). Complexity, interaction and policy research. Policy Sciences,(13):281-295.

  117. Rocke DM, Downs GW. (1980). Time series with episodic disruptions. Analysing Time Series, ed. O.D. Anderson, New York: North-Holland,

  118. Downs GW, Rocke DM. (1979). Interpreting heteroscedasticity. American Journal of Political Science,(23):816-28.

  119. Rocke DM. (1975). p-Groups with abelian centralizers. Proceedings of the London Mathematical Society, 3(30):55-75.

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